It seems impossible for us to read anything without the mind

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It seems impossible for us to read anything without the mind making reference to the framework knowledge_____has already acquired.
A.it B.that D.what
不是that 修饰knowledge,表示“已经获得了的知识”吗?
我们老师说的~但是时间久了，忘记原因了

句子主干是：It seems impossible for us to read anything
只不过后面的独立主格部分比较繁琐：without the mind making reference to the framework knowledge_____has already acquired.
至于空格出该怎么填,第一要明确这个末尾部分的谓语has already acquired是谁发出的.这里对象只有mind思维和knowledge知识,显然是“大脑思维”获得,而非“知识”获得；所以这里的主客体关系是“大脑思维获得知识”,再理解下填入it后句子如何分析：
without the mind making reference to the framework knowledge （it has already acquired）,
it指代mind,并且括号内是以the framework knowledge 为先行词的定语从句,所以这里其实是把that/which省略了（因为在从句中作的是宾语）
原句是：
It seems impossible for us to read anything without the mind making reference to the framework knowledge （which/that）it has already acquired.
翻译：如果思维不能很好的与我们大脑所获得的知识框架联系起来,似乎我们什么也读不懂.

It seems impossible for us to read anything without the mind It ( )impossible for us to meet again without the help of th It's impossible for us to finish the work,_____?反意疑问句 It is impossible for us to finish _____(build) the new schoo It is impossible for us to break the law. We can only break It's impossible for us to finish the work in three days. The road seems to be ------ for us to reach the ----- of it It seems to us that it is impossible for us to stick to just company for a lifet it,without,is,you,for,success,to achieve,impossible,work,连词成英语连词成句：it,is,without,for,you,to,get,success,impossible,worki but for water,it ---impossible to live in the desert